Research topic: Cell Signalling
In order for cells to respond to changes in their external and internal environments, they need an accurate system of communication. Cell signalling provides specific messages about what is taking place and which responses are needed.
About Cell Signalling
In order to properly react to changes in its environment, a cell needs to know both what has occurred and what the response should be. This information is delivered by means of signalling networks and cascades, which can transmit this information from the cell surface to the nucleus.
For example, a cell infected by a virus sends out certain molecules to signal “danger”, which are then recognised by specific molecules on the surface of healthy neighbouring cells. This recognition triggers what is known as a signalling cascade, transmitting the signal step by step through the healthy cell to the nucleus. Once in the nucleus, it initiates an appropriate defence programme, which decreases the chance of getting infected by the virus and helps the immune system to fight the infection.
Cell Signalling Research at BiO
At the Biotechnology Centre of Oslo, the following research groups are investigating various topics within Cell Signalling: