Donaldson group release software to facilitate statistical analysis of protein interaction networks
Antonio Mora has published work on a software package that allows bioinformaticians to access and manipulate protein interaction network data in the statistical analysis environment called R. The paper shows that choices made by analysts with respect to data integration can have an impact on graphical analysis of these networks.
The package allows the analyst to control how these data integration issues are dealt with and communicate them via an R-script written using the iRefR package - this will facilitate communication of methods, reproducibility of network analyses and further modification and comparison of methods by researchers.
Mora A and Donaldson IM. iRefR: an R package to manipulate the iRefIndex consolidated protein interaction database. BMC Bioinformatics (2011) 12, 455 doi:10.1186/1471-2105-12-455