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Donaldson group (2006-2012)

Our primary interests included protein interaction data consolidation, text mining and data mining especially with respect to diseases.

Research focus

The Donaldson Group conducted research and developed tools within the field of Bioinformatics.

Projects 

iRefIndex 

iRefIndex (interaction Reference Index) provides an index of protein interactions available in a number of primary interaction databases including BIND, BioGRID, CORUM, DIP, HPRD, IntAct, MINT, MPact, MPPI and OPHID. This index allows the user to search for a protein and retrieve a non-redundant list of interactors for that protein.
iRefIndex uses the Sequence Global Unique Identifier (SEGUID) to group proteins and interactions into redundant groups. This method allows users to integrate their own data with the iRefIndex in a way that ensures proteins with the exact same sequence will be represented only once.

iRefScape

iRefScape is a plugin for Cytoscape that exposes iRefIndex data as a navigable graphical network.

iRefWeb

iRefWeb provides a searchable web interface to the iRefIndex. iRefWeb also provides visualization of statistics related to iRefIndex and allows users to compare annotation of the same publication by multiple interaction databases.
iRefWeb is a collaborative project with the Wodak group at the Hospital for Sick Children in Toronto.

   
   

DiG: Disease Groups

The Disease Groups project groups together phenotypically related disease-gene associations found in OMIM's Morbid Map. The resulting map of disease genes may be used to explore relationships between disease genes in the human protein-interactome.

   

 

Published Aug 23, 2011 09:46 AM - Last modified Apr 12, 2013 12:57 PM