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Academic Interests

Cancer-related cellular signaling pathways, chemotherapeutic drug-induced apoptosis, cancer therapy, phosphoproteomics.

Positions held

  • 2010 - present:  Postdoctoral research fellow, Thiede Group, Biotechnology Centre of Oslo.

Background

Research:
  • 2006-2009:  Continue as PhD student, Schonberg group, Department of Laboratory Medicine, Children’s and Womens Health, Norwegian University of Science and Technology (NTNU).
    Project: “Do n-3 fatty acids have a potential in treatment of cancer?”
  • 2003-2006:  PhD student, Frengen group, Department of Medical Genetics, University of Oslo.
    Project: “Characterization of oncogene candidates on human chromosome 8q.”
Education:
  • 2009:  PhD, Faculty of Medicine, University of Oslo.
    PhD Thesis:  “The effect of n-3 polyunsaturated fatty acids on cellular metabolism and signaling pathways in human colon cancer cells”
  • 2003:  Master in Chemistry and Biotechnology, Norwegian University of Science and Technology (NTNU).
    MSc thesis: “Down regulation of the expression of cancer relevant genes by introduction of siRNA constructs in human cell lines”. 

 

Tags: Cancer, Cell signalling, Apoptosis

Publications

Full list of publications (PubMed listing)

  • Slagsvold, Jens Erik; Pettersen, Caroline Hild; Størvold, Gro Leite; Follestad, Turid; Krokan, Hans Einar & Schønberg, Svanhild Margrethe Arentz (2010). DHA alters expression of target proteins of cancer therapy in chemotherapy resistant SW620 colon cancer cells. Nutrition and Cancer.  ISSN 0163-5581.  62(5), s 611- 621 . doi: 10.1080/01635580903532366
  • Askautrud, Hanne Arenberg; Gjernes, Elisabet; Størvold, Gro Leite; Lindeberg, Mona Mari; Thorsen, J; Prydz, Hans Peter B & Frengen, Eirik (2009). Regulated expression of a transgene introduced on an oriP/EBNA-1 PAC shuttle vector into human cells. BMC Biotechnology.  ISSN 1472-6750.  9 . doi: 10.1186/1472-6750-9-88
  • Størvold, Gro Leite; Fleten, Karianne Giller; Olsen, Cathrine Goberg; Follestad, Turid; Krokan, Hans Einar & Schønberg, Svanhild Margrethe Arentz (2009). Docosahexaenoic acid activates some SREBP-2 targets independent of cholesterol and ER stress in SW620 colon cancer cells. Lipids.  ISSN 0024-4201.  44(8), s 673- 683 . doi: 10.1007/s11745-009-3324-4
  • Jakobsen, CH; Pettersen, Caroline Hild; Størvold, Gro Leite; Bremseth, Hilde; Follestad, Turid; Sand, Kristin; Mack, Merete; Olsen, Karina Standahl; Lundemo, Anne Gøril; Iversen, Jens Gustav; Krokan, Hans Einar; Schonberg, SA & Schønberg, Svanhild Margrethe Arentz (2008). DHA induces ER stress and growth arrest in human colon cancer cells: association with cholesterol and calcium homeostasis. Journal of Lipid Research.  ISSN 0022-2275.  49, s 2089- 2100 . doi: 10.1194/jlr.M700389-JLR200
  • Størvold, Gro Leite; Gjernes, Elisabet; Askautrud, Hanne Arenberg; Børresen-Dale, Anne-Lise; Perou, Charles M & Frengen, Eirik (2007). A retroviral vector for siRNA expression in mammalian cells. Molecular Biotechnology.  ISSN 1073-6085.  35(3), s 275- 282

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  • Størvold, Gro Leite (2009). The effect of n-3 polyunsaturated fatty acids on cellular metabolism and signaling pathways in human colon cancer cells..
  • Slagsvold, Jens Erik; Pettersen, Caroline Hild; Størvold, Gro Leite & Schønberg, Svanhild Margrethe Arentz (2008). Omega-3 fettsyrer påvirker uttrykket av målproteiner for cytostatika i colonkreft celler.
  • Bremseth, Hilde; Jakobsen, Caroline Hild; Lundemo, Anne Gøril; Størvold, Gro Leite; Krokan, Hans Einar & Schønberg, Svanhild Margrethe Arentz (2007). Stress protein activation by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells.
  • Jakobsen, Caroline Hild; Bremseth, Hilde; Størvold, Gro Leite; Olsen, Karina Standahl; Follestad, Turid; Lundemo, Anne Gøril; Krokan, Hans Einar & Schønberg, Svanhild Margrethe Arentz (2007). DHA-induced growth inhibition of cancer cells is associated with disturbances in cholesterol metabolism, calcium homeostasis and induction of ER stress.
  • Jakobsen, Caroline Hild; Størvold, Gro Leite; Bremseth, Hilde; Krokan, Hans Einar & Schønberg, Svanhild Margrethe Arentz (2007). DHA induces ER stress, cell cycle arrest and disturbance in cholesterol homeostasis in colon cancer cells.
  • Jakobsen, Caroline Hild; Størvold, Gro Leite; Bremseth, Hilde & Schønberg, Svanhild Margrethe Arentz (2007). Har n-3 fettsyrer et potensiale i behandling av kreft? -Effekt på cellesyklus, lipid metabolisme og oxidativt stress.
  • Jakobsen, Caroline Hild; Størvold, Gro Leite & Slagsvold, Jens Erik (2007). Omega-3 fatty acids - methods for verification of anti-cancer actions.
  • Størvold, Gro Leite (2007). The 2nd RNA Interference Conference. NBS-nytt.  ISSN 0801-3535.  31(2), s 21- 23
  • Størvold, Gro Leite; Jakobsen, Caroline Hild; Bremseth, Hilde & Schønberg, Svanhild Margrethe Arentz (2007). DHA induces disturbance in cholesterol homeostasis, ER stress and cell cycle arrest in colon cancer cells.
  • Størvold, Gro Leite; Schønberg, Svanhild Margrethe Arentz; Jakobsen, Caroline Hild & Bremseth, Hilde (2007). Har n-3 fettsyrer et potensiale i behandling av kreft?.
  • Askautrud, Hanne Arenberg; Gjernes, Elisabet; Størvold, Gro Leite; Børresen-Dale, Anne-Lise & Frengen, Eirik (2006). Hypoxia response in breast cancer models. Mechanisms and Models of Cancer..
  • Gjernes, Elisabet; Størvold, Gro Leite; Askautrud, Hanne Arenberg; Børresen-Dale, Anne-Lise; Perou, Charles M & Frengen, Eirik (2005). Functional characterization of genes involved in the development of breast cancer.

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Published Aug 22, 2011 10:51 AM - Last modified Sep 5, 2012 12:52 PM

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